产品货号：
GS4499
中文名称：
重组小鼠CXCL16
英文名称：
Recombinant Murine CXCL16
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 9.9kDa,a single non-glycosylated polypeptide chain containing 88 amino acids.
储存条件：冷冻（-20℃）
概述
CXCL16 is a member of the CXC chemokine family.Larger than other chemokines,it is one of the only two transmembrane chemokines in the family and the other is CX3CL1.Mouse CXCL16 has 246 a.a.and consists of a 26 a.a.residue putative signal peptide,an 88 a.a.residue chemokine domain,an 87 a.a.residue mucin-like spacer region,a 22 a.a.residue transmembrane domain,and a 23 a.a.residue cytoplasmic tail.Mouse CXCL16 shares 70%sequence identity with human CXCL16 in chemokine domain.CXCL16 interacts with the chemokine receptor CXCR6,also known as Bonzo.Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha.Functions of CXCL16 include inducing a strong chemotactic response and calcium mobilization.CXCL16 also acts as a scavenger receptor on macrophages,which specifically binds to OxLDL(oxidized low density lipoprotein),suggesting that it may be involved in pathophysiology such as atherogenesis.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠CXCL16，CXCL16, Murine，Recombinant Murine CXCL16
储存条件：冷冻（-20℃）
概述
CXCL16 is a member of the CXC chemokine family.Larger than other chemokines,it is one of the only two transmembrane chemokines in the family and the other is CX3CL1.Mouse CXCL16 has 246 a.a.and consists of a 26 a.a.residue putative signal peptide,an 88 a.a.residue chemokine domain,an 87 a.a.residue mucin-like spacer region,a 22 a.a.residue transmembrane domain,and a 23 a.a.residue cytoplasmic tail.Mouse CXCL16 shares 70%sequence identity with human CXCL16 in chemokine domain.CXCL16 interacts with the chemokine receptor CXCR6,also known as Bonzo.Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha.Functions of CXCL16 include inducing a strong chemotactic response and calcium mobilization.CXCL16 also acts as a scavenger receptor on macrophages,which specifically binds to OxLDL(oxidized low density lipoprotein),suggesting that it may be involved in pathophysiology such as atherogenesis.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration of 20-1000ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS. |
| 内毒素 | Less than 1 EU/μg of rMuCXCL16 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP |
相关搜索：重组小鼠CXCL16，CXCL16, Murine，Recombinant Murine CXCL16